Saturday, November 15, 2014

Journal Club: PET/CT versus MRI in Breast Cancer

QUESTION. What is the value of PET/CT and MRI in predicting subtypes of breast cancer?

METHODS. a retrospective review was done.

RESULTS: high SUV-max was associated with a high Ki-67 index, ER-negative status, and PR-negative status. SUVmax was significantly lower for luminal A than non-luminal A tumors. A cutoff value of 5.4 yielded 79% sensitivity and 68% specificity for prediction that a tumor was the luminal A subtype.

CONCLUSION. FDG PET/CT findings may contribute to differentiation of the luminal A and non-luminal A subtypes of invasive breast cancer.

AJR Am J Roentgenol. 2014 Aug;203(2):272-279