OBJECTIVE. The objective of this study was to optimize CT protocols for whole-body PET/CT
MATERIALS AND METHODS. Effective dose from the CT component of the examination was estimated using dose-length product (DLP) values from reports generated by the scanner and anatomy-specific conversion factors. Twenty-six patients who underwent studies before and after the optimization were included in an analysis of image quality. The studies were randomized and blinded for an experienced PET and CT reader who graded the imaging quality of anatomic structures.
RESULTS. CT protocol optimization resulted in a 32% reduction of the mean CT radiation dose: The mean effective dose was reduced from 8.1 to 5.5 mSv. The blinded analysis of image quality showed no clinically significant degradation of the lower-dose studies.
CONCLUSION. The results of this study showed that optimization of CT acquisition can effectively reduce radiation dose in a whole-body PET/CT examination without significantly sacrificing image quality.
AJR Am J Roentgenol. 2013 Aug;201(2):257-63