Monday, March 17, 2014

Journal Club Article: Azithromycin and Levofloxacin Use and Increased Risk of Cardiac Arrhythmia and Death

TITLE: Azithromycin and Levofloxacin Use and Increased Risk of Cardiac Arrhythmia and Death

CITATION:  Ann Fam Med. 2014 Mar-Apr;12(2):121-7

FULL TEXT LINK:  http://goo.gl/nBJE2c

Q1: In order to compare the side-effects of the antibiotics against one another, we need to ensure that the patient groups are similar. Are they? #pcmjc

Q2: In your practice, are you more likely to prescribe amoxicillin to patients that are less ill, and azithromycin to more ill patients? #pcmjc

Q3: Was the author's statistical handling of confounding variables legitimate? http://bit.ly/OprrBN #pcmjc

Q4: Even though the authors corrected for confounding variables, does this mean that the sicker patients should get amoxicillin instead of levofloxacin? #pcmjc

Q5: Will this article change your practice? Why or why not?  #pcmjc

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